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Paolo Rossi Castelli01 Jun 20181 min read

A new gel repairs stroke damage (in animals)


As researchers reported in the journal Nature Materials, the gel used contained pro-angiogenetic and anti-inflammatory substances (i.e. favourable to the formation of new blood vessels). In addition, the gel possessed physical and chemical properties that facilitated the construction of an effective structure for the creation of new tissue. The combination of all these elements created a micro-environment capable of facilitating neuronal regeneration, which is often impossible, or in any case very rare. Sixteen weeks after treatment on animals – explain researchers – the brain cavities that are normally formed following a stroke, containing non-vital scar tissue, were full of veins and nervous tissue composed of interconnecting cells: something that had never been seen before. In addition, the animals showed an improvement in their search for food, a parameter that demonstrates motor rehabilitation and therefore the recovery of nervous cells.

It is not yet completely clear how the gel manages to distribute the synthesis of new nervous cells, but researchers will continue to study the phenomenon, in the hope that this mix will soon be able to be tested on humans.

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Paolo Rossi Castelli

A professional journalist, Paolo has been involved in scientific popularisation for many years, especially in the field of medicine and biology. He is the creator of Sportello Cancro, the site created by corriere.it on oncology in collaboration with the Umberto Veronesi Foundation. He has written for the Science pages of Corriere della Sera and other national newspapers. He is founder and director of PRC-Comunicare la scienza.

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